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3:423, DDS, PhD, Charles Sfeir, DDS, PhD, Kodi Azari, MD, Sarah Holland, MD, and Jeffrey O. Dermatol Surg 1997;23(12):11511160 16. Two general molecular stlck of antagonism are orthosteric (where the agonist and antagonist compete for the same binding site on the protein) and allosteric (where there are separate binding sites on the receptor for both the agonist and the antagonist and the effects of the antagonist are transmitted through the protein).
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